Dota 2 is the game Artifact uses as base for its lore and game design.
Based on the Warcraft III mod "Defense of the Ancients", Dota 2 is a by Valve Corporation developed and published MOBA game.
The development of Dota 2 started after IceFrog (the developer of Defense of the Ancients) got hired by Valve.
In Dota 2, two teams face off against each other with five player-controlled heroes to destroy the enemies ancient.
Dota 2 and ArtifactEdit
At the Artifact press conference at 2018-03-08, Gabe Newell emphasized that Artifact wasn't developed to be a Dota 2 card game, but rather that the Dota universe served best as a base to Artifact's lore: